1. 重组蛋白
  2. Enzymes & Regulators
  3. Protease Inhibitors
  4. Inter-Alpha-Trypsin Inhibitors (ITI)
  5. ITIH5
  6. ITIH5 蛋白, Human (HEK293, His-hFc)

ITIH5 蛋白, Human (HEK293, His-hFc)

目录号: HY-P701322
COA 产品使用指南

ITIH5 蛋白被鉴定为潜在的肿瘤抑制因子,表明其在控制肿瘤发生中的关键作用。作为一种肿瘤抑制因子,ITIH5 有望抵消不受控制的细胞生长并抑制或调节肿瘤发展的关键途径。ITIH5 蛋白, Human (HEK293, His-hFc) 是重组的 ITIH5 蛋白,由 HEK293 表达,带有 C-hFc 标签。ITIH5 蛋白, Human (HEK293, His-hFc) 全长 127 个氨基酸,分子量约为 ~50 kDa。

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规格 价格 是否有货 数量
20 μg ¥1820 In-stock
50 μg ¥4000 In-stock
100 μg   询价  

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描述

The ITIH5 protein was identified as a potential tumor suppressor, indicating its critical role in controlling tumorigenesis. As a tumor suppressor, ITIH5 is expected to counteract uncontrolled cell growth and inhibit or regulate key pathways in tumor development. ITIH5 Protein, Human (HEK293, His-hFc) is the recombinant human-derived ITIH5 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

ITIH5 蛋白作为一种潜在的肿瘤抑制因子出现,表明在调节肿瘤发生中发挥着至关重要的作用。其作为肿瘤抑制因子的指定意味着具有抵消癌细胞不受控制的细胞生长特征的能力。通过抑制或调节肿瘤发展中涉及的关键途径,ITIH5可能有助于维持正常细胞功能和预防恶性转化。ITIH5 作为假定的肿瘤抑制因子的特征强调了它在复杂的细胞调节机制网络中的重要性,需要进一步研究其具体的作用机制和在癌症管理中的潜在治疗意义。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q86UX2 (V35-E161)

基因 ID

80760

蛋白结构
N-term
ITIH5 (V35-E161)
Accession # Q86UX2
hFc
C-term
同用名
ITI heavy chain H5; ITI-HC5; Inter-alpha-inhibitor heavy chain 5; ITIH5
氨基酸序列

VPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEE

分子量

Approximately 50 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

ITIH5 Protein, Human (HEK293, His-hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ITIH5 Protein, Human (HEK293, His-hFc)
目录号:
HY-P701322
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