Kallikrein-4 蛋白, Human (254a.a, HEK293, His)

Kallikrein-4 Protein is crucial in enamel formation, particularly during tooth maturation, playing a significant role in clearing enamel proteins and contributing to the structural patterning of the crystalline matrix. Its involvement underscores its importance in intricate tooth development processes, emphasizing its role in proper dental structure and function. Kallikrein-4 Protein, Human (254a.a, HEK293, His) is the recombinant human-derived Kallikrein-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kallikrein-4 Protein, Human (254a.a, HEK293, His) is 254 a.a., with molecular weight of 30-35 kDa.

Kallikrein-4 蛋白在牙釉质形成中发挥着重要作用，特别是在牙齿发育的成熟阶段。它对于牙釉质蛋白的清除至关重要，并有助于晶体基质的正常结构模式。这强调了该蛋白质在牙齿发育和牙釉质成熟的复杂过程中的关键参与，强调了它对于适当的牙齿结构和功能的重要性。

Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >250 pmol/min/μg.
(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)

Human

HEK293

C-His

Q9Y5K2 (M1-S254)

9622  [NCBI]

30-35 kDa

Greater than 90% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.