Klrb1a 蛋白, Mouse (HEK293, His)

The Klrb1a protein is critical for stimulating NK cell cytotoxicity and contributes to immune defense mechanisms.Klrb1a exists as a homodimer with disulfide bonds and complexly regulates NK cell activity.Klrb1a Protein, Mouse (HEK293, His) is the recombinant mouse-derived Klrb1a protein, expressed by HEK293 , with N-His labeled tag.

Klrb1a 蛋白在刺激自然杀伤 (NK) 细胞的细胞毒性方面发挥着关键作用，有助于免疫系统的防御机制。Klrb1a 作为具有二硫键的同型二聚体存在，复杂地参与调节 NK 细胞的活性。它与酪氨酸激酶 LCK 的相互作用表明了增强 NK 细胞毒性的信号转导或调节过程的潜在机制。通过这些分子相互作用，Klrb1a 在免疫反应的协调中发挥着关键作用，特别是在 NK 细胞的激活和调节中，从而有助于人体防御各种威胁。

Mouse

HEK293

N-His

P27811 (Q67-H227)

17057  [NCBI]

QKPSIEKCYVLIQENLNKTTDCSAKLECPQDWLSHRDKCFHVSHVSNTWEEGLVDCDGKGATLMLIQDQEELRFLLDSIKEKYNSFWIGLRYTLPDMNWKWINGSTLNSDVLKITDDTENDSCAAISGDKVTFESCNSDNRWICQKELYHETLSNYVGYGH

Approximately 24-33 kDa due to the glycosylation

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.