LAIR2 蛋白, Human (HEK293)

Leukocyte-associated immunoglobulin-like receptor 2 is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 Protein, Human (HEK293) is the recombinant human-derived LAIR2 protein, expressed by HEK293 , with tag free.

Leukocyte-associated immunoglobulin-like receptor 2 是免疫球蛋白超家族成员之一。Leukocyte-associated immunoglobulin-like receptor 2 是一种可溶性受体，可能在胎盘植入期间抑制胶原诱导的血小板聚集和血管形成中发挥作用。Leukocyte-associated immunoglobulin-like receptor 2 定位于19q13.4区域，称为白细胞受体簇，该区域包含免疫球蛋白超家族中的29个基因^[1][2][3]。

Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 5 x 10⁴ cells/well are added to rhLAIR-2 coated plates (50 µg/mL with 100 µL/well), approximately 43.3% will adhere after 10 minutes at 37°C.

Human

HEK293

Tag Free

Q6ISS4-1 (Q22-P152)

3904  [NCBI]

QEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRLEREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLVKESSGGPDSPDTEPGSSAGTVPGTEASGFDAP

Approximately 22 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE. The apparent molecular mass of protein is approximately 22 kDa under reducing SDS-PAGE due to glycosylation.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.