LIFR 蛋白, Human (HEK293, Fc)

LIFR Protein, a signal-transducing molecule, potentially shares a common pathway with IL6ST. Its soluble form inhibits LIF binding to target cell receptors, reducing biological activity. LIFR forms a heterodimer with IL6ST, interacting with the CNTF and CNTFR complex, implying potential crosstalk and collaborative actions in cellular processes. LIFR Protein, Human (HEK293, Fc) is the recombinant human-derived LIFR protein, expressed by HEK293 , with C-hFc labeled tag.

LIFR 蛋白作为信号转导分子，可能与 IL6ST 具有共同的通路。其可溶形式可作为抑制剂，阻断 LIF 与靶细胞上受体的结合，从而抑制其生物活性。LIFR 与 IL6ST 形成异二聚体，并且该异二聚体与 CNTF 和 CNTFR 形成的复合物相互作用，表明细胞过程中潜在的串扰和协作作用。

Human

HEK293

C-hFc

P42702-1/NP_001121143.1 (M45-S833)

3977  [NCBI]

Approximately 116.1 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.