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  4. LRG1 蛋白, Cynomolgus (HEK293, His)

LRG1 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700782
产品使用指南

LRG1 是富含亮氨酸重复序列 (LRR) 的蛋白家族成员，参与蛋白-蛋白相互作用、信号转导和细胞粘附和发育。LRG1 通过引起内皮细胞中转化生长因子 β (TGF-β) 信号的开关，参与促进新生血管。LRG1 通过激活 FAK/AKT 信号通路参与卵巢癌的进展。LRG1 蛋白, Cynomolgus (HEK293, His) 是重组的 LRG1 蛋白，由 HEK293 表达，带有 C-His 标签。LRG1 蛋白, Cynomolgus (HEK293, His) 全长 312 个氨基酸，分子量为 50-60 kDa。

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100 μg   询价  

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描述

LRG1 is a member of the leucine-rich repeat sequence (LRR) family of proteins involved in protein-protein interactions, signal transduction, and cell adhesion and development. LRG1 is involved in promoting neovascularization by causing the switching of transforming growth factor β (TGF-β) signaling in endothelial cells. LRG1 is involved in ovarian cancer progression by activating the FAK/AKT signaling pathway. LRG1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LRG1 protein, expressed by HEK293 , with C-His labeled tag. The total length of LRG1 Protein, Cynomolgus (HEK293, His) is 312 a.a., with molecular weight of 50-60 kDa.
研究背景

LRG1 是富含亮氨酸重复序列 (LRR) 的蛋白家族成员，参与蛋白-蛋白相互作用、信号转导和细胞粘附和发育。LRG1 通过引起内皮细胞中转化生长因子 β (TGF-β) 信号的开关，参与促进新生血管 (新血管生长)。LRG1 结合副受体内啡肽并通过 ALK1-Smad1/5/8 途径促进信号传导。LRG1 通过激活 FAK/AKT 信号通路参与卵巢癌的进展。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

A0A2K5VVA4 (V72-Q383)
基因 ID

102118680
蛋白结构
N-term
LRG1 (V72-Q383)
Accession # A0A2K5VVA4
His
C-term
同用名
Leucine-rich alpha-2-glycoprotein; LRG; LRG1
分子量

50-60 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

LRG1 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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