1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CC Chemokines
  5. CCL12
  6. MCP-5/CCL12 蛋白, Rat

MCP-5/CCL12 蛋白属于间分泌β家族,对于参与细胞间通讯和免疫反应的趋化因子至关重要。在这个家族中,MCP-5/CCL12 可能在调节炎症过程和细胞相互作用中发挥作用。MCP-5/CCL12 蛋白, Rat 是重组的 MCP-5/CCL12 蛋白,由 E. coli 表达,不带标签。MCP-5/CCL12 蛋白, Rat 全长 68 个氨基酸,分子量约为 ~7.9 kDa。

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The MCP-5/CCL12 protein belongs to the intercrine beta family and is essential for chemokines involved in intercellular communication and immune responses. In this family, MCP-5/CCL12 may play a role in regulating inflammatory processes and cellular interactions. MCP-5/CCL12 Protein, Rat is the recombinant rat-derived MCP-5/CCL12 protein, expressed by E. coli , with tag free. The total length of MCP-5/CCL12 Protein, Rat is 68 a.a., with molecular weight of ~7.9 kDa.

研究背景

MCP-5/CCL12 蛋白是间分泌 β(趋化因子 CC)家族的成员,将其归入一组以其在细胞间通讯和免疫反应中的作用而闻名的趋化因子。作为间分泌 β 家族的一部分,MCP-5/CCL12 可能参与炎症过程和细胞相互作用的调节。进一步的研究对于在趋化因子 CC 家族的更广泛背景下揭示 MCP-5/CCL12 的具体功能和影响至关重要,阐明其在介导免疫反应和促进细胞间信号传导的复杂网络中的重要性。

生物活性

Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/mL.

种属

Rat

表达系统

E. coli

标签

Tag Free

蛋白编号

Q9QZU1 (G14-A81)

基因 ID

/

蛋白结构
N-term
CCL12 (G14-A81)
Accession # Q9QZU1
C-term
中文名
重组鼠MCP-5蛋白
同用名
C-C motif chemokine; CCL12
氨基酸序列

GPYGANVEDSICCQDYIRHPLPPRFVKEFYWTSKSCRKPGVVLITIKNRDICADPRMLWVKKILHKLA

分子量

Approximately 7.9 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in sterile distilled water.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MCP-5/CCL12 Protein, Rat
目录号:
HY-P71903
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