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  4. MFAP4 蛋白, Cynomolgus (HEK293, His)

MFAP4 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700873
产品使用指南

MFAP4 是微原纤维相关糖蛋白 (MFAP) 家族的一部分，参与细胞粘附，细胞间相互作用以及弹性纤维的组装和/或维持。MFAP4 缺乏通过抑制 NF-κB 和 TGF-β/Smad 信号通路减轻肾纤维化。MFAP4 是人类癌症的新型生物标志物。MFAP4 蛋白, Cynomolgus (HEK293, His) 是重组的 MFAP4 蛋白，由 HEK293 表达，带有 C-His 标签。MFAP4 蛋白, Cynomolgus (HEK293, His) 全长 234 个氨基酸，分子量为 35-40 kDa。

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描述

MFAP4 is part of the microfibril-associated glycoprotein (MFAP) family and is involved in cell adhesion, cell-cell interactions, and the assembly and/or maintenance of elastic fibers. MFAP4 deficiency alleviates renal fibrosis by inhibiting NF-κB and TGF-β/Smad signaling pathways. MFAP4 is a novel biomarker for human cancer. MFAP4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MFAP4 protein, expressed by HEK293 , with C-His labeled tag. The total length of MFAP4 Protein, Cynomolgus (HEK293, His) is 234 a.a., with molecular weight of 35-40 kDa.
研究背景

MFAP4 是微原纤维相关糖蛋白 (MFAP) 家族的一部分，参与细胞粘附，细胞间相互作用以及弹性纤维的组装和/或维持。MFAP4 缺乏通过抑制 NF-κB 和 TGF-β/Smad 信号通路减轻肾纤维化。MFAP4 可促进血管平滑肌迁移、增殖，加速新生内膜形成。MFAP4 也可作为开发人类癌症治疗的新型生物标志物。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

A0A2K5TQS8 (V60-A293)
基因 ID

/
蛋白结构
N-term
MFAP4 (V60-A293)
Accession # A0A2K5TQS8
His
C-term
同用名
Microfibril-associated glycoprotein 4; Mfap4
分子量

35-40 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

MFAP4 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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