MGLL 蛋白, Human (His)

MGLL proteins convert monoacylglycerides into free fatty acids and glycerol. MGLL Protein, Human (His) is the recombinant human-derived MGLL protein, expressed by E. coli , with N-6*His labeled tag. The total length of MGLL Protein, Human (His) is 302 a.a., .

MGLL 是脂质代谢中的关键酶，是单酰基甘油酯转化为游离脂肪酸和甘油的关键催化剂，其在各种研究中所记录的作用证明了这一点。除了参与脂质代谢之外，MGLL 还具有水解内源性大麻素 2-花生四烯酰甘油的能力，从而对内源性大麻素信号传导的复杂调节做出重大贡献，并影响伤害知觉和疼痛感知。值得注意的是，MGLL 在调节脂肪酸水平方面发挥着至关重要的作用，脂肪酸是重要的信号分子，对多种细胞功能有影响。这种酶的影响延伸到癌症生物学，根据各种研究表明，它与促进癌细胞迁移、侵袭和整体肿瘤生长有关。

Human

E. coli

N-6*His

Q99685 (P2-P303)

11343

Approximately 35.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.22 μm filtered solution of 50 mM HEPES, pH 7.5, 200 mM NaCl, 20% glycerol.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.