1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. MGLL 蛋白, Human

MGLL 蛋白将单酰基甘油酯转化为游离脂肪酸和甘油。MGLL 蛋白, Human 是重组的 MGLL 蛋白,由 E. coli 表达,不带标签。MGLL 蛋白, Human 全长 302 个氨基酸。

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描述

MGLL proteins convert monoacylglycerides into free fatty acids and glycerol. MGLL Protein, Human is the recombinant human-derived MGLL protein, expressed by E. coli , with tag free. The total length of MGLL Protein, Human is 302 a.a., .

研究背景

MGLL 是脂质代谢中的关键酶,是单酰基甘油酯转化为游离脂肪酸和甘油的关键催化剂,其在各种研究中所记录的作用证明了这一点。除了参与脂质代谢之外,MGLL 还具有水解内源性大麻素 2-花生四烯酰甘油的能力,从而对内源性大麻素信号传导的复杂调节做出重大贡献,并影响伤害知觉和疼痛感知。值得注意的是,MGLL 在调节脂肪酸水平方面发挥着至关重要的作用,脂肪酸是重要的信号分子,对多种细胞功能有影响。这种酶的影响延伸到癌症生物学,根据各种研究表明,它与促进癌细胞迁移、侵袭和整体肿瘤生长有关。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

Q99685 (P2-P303)

基因 ID

11343

蛋白结构
N-term
MGLL (P2-P303)
Accession # Q99685
C-term
中文名
MGLL 蛋白
同用名
MGLL; Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

MGLL Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MGLL Protein, Human
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HY-P701984
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