MKNK1 蛋白, Human (Sf9, GST)

MKNK1 (MAP Kinase Interacting Serine/Threonine Kinase 1) plays a central role in coordinating cellular responses to environmental stress and cytokines. It exerts regulatory control over translation processes by phosphorylating EIF4E, enhancing its affinity for mRNA cap structures with 7-methylguanosine. This highlights MKNK1's crucial involvement in finely tuning translation machinery in response to diverse cellular stimuli. MKNK1 Protein, Human (Sf9, GST) is the recombinant human-derived MKNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MKNK1 Protein, Human (Sf9, GST) is 424 a.a., .

MKNK1（MAP 激酶相互作用丝氨酸/苏氨酸激酶 1）在协调细胞对环境压力和细胞因子的反应中发挥着关键作用。它的调节影响延伸到翻译过程，通过磷酸化 EIF4E 来发挥控制作用。这种磷酸化事件增强了 EIF4E 对含有 7-甲基鸟苷的 mRNA 帽的亲和力，阐明了 MKNK1 在微调翻译机制以响应不同细胞刺激中的作用。

Human

Sf9 insect cells

N-GST

Q9BUB5 (M1-L424)

8569

Approximately 73.9 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, pH7.5, 150 mM NaCl, 10% glycerol, 0.05% Brij, 1 mM DTT.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.