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  3. MOG 蛋白, Human (HEK293, C-His)

MOG 蛋白, Human (HEK293, C-His)

目录号: HY-P70845A
COA 产品使用指南

MOG 蛋白在细胞间均匀粘附、促进重要连接方面发挥着关键作用。作为髓磷脂的一个次要但不可或缺的组成部分,它有助于其基本的完成和维护。MOG 蛋白, Human (HEK293, C-His) 是重组的 MOG 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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5 μg ¥500 In-stock
10 μg ¥800 In-stock
50 μg ¥2200 In-stock
100 μg ¥3500 询价
250 μg ¥7500 In-stock
500 μg ¥12000 询价
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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

MOG proteins play a key role in homogeneous cell-to-cell adhesion, promoting important junctions. As a minor but integral component of myelin, it contributes to its underlying completion and maintenance. MOG Protein, Human (HEK293,C-His) is the recombinant human-derived MOG protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

MOG 蛋白在促进同质细胞间粘附、促进细胞之间的重要连接方面发挥着关键作用。作为髓鞘的一个次要但不可或缺的组成部分,MOG 蛋白与这一重要神经结构的潜在完成和维护有关。它的影响超出了结构支持范围,因为它还可能参与介导细胞间的通讯。值得注意的是,在微生物感染期间,MOG 蛋白充当风疹病毒的受体,强调其在生理髓磷脂功能和对病毒挑战的病理反应方面的多方面参与。

生物活性

Measured in a cell proliferation assay using SH-SY5Y cells. The ED50 for this effect is 0.9783 μg/mL, corresponding to a specific activity is 1.022×103 units/mg.

  • Measured in a cell proliferation assay using SH-SY5Y cells. The ED50 for this effect is 0.9783 μg/mL, corresponding to a specific activity is 1.022×103 units/mg.
种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q16653-1 (G30-G154)

基因 ID

4340

蛋白结构
N-term
MOG (G30-G154)
Accession # Q16653-1
6*His
C-term
同用名
Myelin-Oligodendrocyte Glycoprotein; MOG
氨基酸序列

GQFRVIGPRHPIRALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG

分子量

Approximately 19-25 kDa due to the glycosylation.

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

MOG Protein, Human (HEK293, C-His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MOG Protein, Human (HEK293, C-His)
目录号:
HY-P70845A
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