NAALADL1 蛋白, Mouse (HEK293, His)

The NAALADL1 protein is an aminopeptidase that efficiently hydrolyzes a variety of substrates, except those with specific amino acid positions. It has lower activity against substrates containing Asp or Glu at the P2' position or Pro at the P3' position. NAALADL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NAALADL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of NAALADL1 Protein, Mouse (HEK293, His) is 717 a.a., with molecular weight of ~110 kDa.

NAALADL1 蛋白是一种氨肽酶，具有广泛的底物特异性。它可以有效地水解多种底物，但 P2' 位具有 Asp 或 Glu 或 P3' 位具有 Pro 的底物除外，这些底物的活性较低。此外，当底物 P3' 位置上同时含有 Pro 且 P2' 位置上含有 Asp 或 Glu 时，NAALADL1 缺乏酶活性。值得注意的是，它不具有羧肽酶活性或二肽基肽酶 IV 型活性。

Measured by its binding ability in a functional ELISA. Immobilized Mouse NAALADL1, at 2μg/mL (100μL/well) can bind Anti-NAALADL1 antibody. The ED₅₀ for this effect is 0.2066 μg/mL.

• 
  Measured by its binding ability in a functional ELISA. Immobilized Mouse NAALADL1, at 2 μg/mL (100 μL/well) can bind Anti-NAALADL1 antibody. The ED₅₀ for this effect is 0.2066 μg/mL.

Mouse

HEK293

N-His

Q7M758 (P29-L745)

381204  [NCBI]

PKATSPLTSSTSDSQDLDLAILDSVMGQLDASRIRENLRELSKEPHVATSPRDEALVQLLLGRWKDTATGLDSAKTYEYRVLLSFPNAEQPNSVEVVGPNGTTFHSFQPFEKNLTGEQAGPNVLQPYAAYAPPGTPKGLLVYANQGSEEDFKELETQGINLEGTIALTRYGGVGRGAKAINAAKHGVVGVLVYTDPGDINDGKSLPNETFPNSWRLPPSGVERGSYYEYFGDPLTPYLPAHPSSFRLDPHNTSGFPPIPTQPIGFEDARDLLCNLTGTSAPAFWQGALGCEYKLGPGFEPNGSFPAGSEVKVSVHNRLELRTSSNVLGIIQGAVEPDRYVIYGNHRDSWVHGAVDPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVAYINVDISVFSNATLRAQGTPPVQSVIFSATKEISAPGSSGLSIYDNWIRYTNRTSPVYGLVPSLGTLGAGSDYAAFVHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLQSFLQAAQEALGTQLEKQNISLGPLVTAVANFKAAAASLGEHILTLQKSSPDPLQVRMVNDQLMLLERAFLNPRAFPEERHYSHVLWAPNTASVDTFPGLANAYAKAQEINSGSEAWAEVQRQLSIVVTALEGAAATLVPVADL

Approximately 95-125 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.