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  4. NBL1 蛋白, Human (HEK293, Fc)

NBL1 蛋白, Human (HEK293, Fc)

目录号: HY-P74737
产品使用指南

NBL1蛋白被认为是神经母细胞瘤中潜在的抑癌基因，在抑制细胞进入转化过程中关键的G1/S阶段中发挥着至关重要的作用。NBL1 作为同二聚体发挥作用，强调其参与细胞转化的调控机制，并强调其对维持正常细胞生长控制的潜在贡献。NBL1 蛋白, Human (HEK293, Fc) 是重组的 NBL1 蛋白，由 HEK293 表达，带有 C-hFc 标签。NBL1 蛋白, Human (HEK293, Fc) 全长 165 个氨基酸，分子量为 55-60 kDa。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

NBL1 protein, identified as a potential tumor suppressor gene in neuroblastoma, plays a crucial role in inhibiting cells from progressing into the critical G1/S stage of the transformation process. Functioning as a homodimer, NBL1 underscores its involvement in regulatory mechanisms governing cellular transformation and emphasizes its potential contributions to maintaining normal cellular growth control. NBL1 Protein, Human (HEK293, Fc) is the recombinant human-derived NBL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NBL1 Protein, Human (HEK293, Fc) is 165 a.a., with molecular weight of 55-60 kDa.
研究背景

NBL1 蛋白作为神经母细胞瘤中潜在的抑癌基因出现，表明其在阻止细胞进入转化过程的关键 G1/S 阶段方面发挥着关键作用。值得注意的是，NBL1 作为同二聚体发挥作用，强调了它参与控制细胞转化的调节机制，并强调了它对维持正常细胞生长控制的潜在贡献。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

P41271 (A17-D181)
基因 ID

100532736  [NCBI]/4681  [NCBI]
蛋白结构
N-term
NBL1 (A17-D181)
Accession # P41271
hFc
C-term
同用名
Neuroblastoma suppressor of tumorigenicity 1; Protein N03; NBL1; DAN; DAND1
分子量

55-60 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

NBL1 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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