2. 重组蛋白
  3. CD Antigens
  4. NK Cell CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins
  5. NCAM-1/CD56
  6. NCAM-1/CD56 蛋白, Cynomolgus (HEK293, His)

NCAM-1/CD56 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P701026
COA 产品使用指南

NCAM-1/CD56 蛋白是一种重要的细胞粘附分子，参与神经元-神经元粘附、神经突束颤和神经突生长。它与 MDK 相互作用，并与 SLC39A6 和 SLC39A10 形成复合物，复杂地调节 NCAM-1 磷酸化。NCAM-1/CD56 蛋白, Cynomolgus (HEK293, His) 是重组的 NCAM-1/CD56 蛋白，由 HEK293 表达，带有 C-His 标签。NCAM-1/CD56 蛋白, Cynomolgus (HEK293, His) 全长 699 个氨基酸，分子量为 95-115 kDa。

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规格 价格 是否有货 数量
20 μg ￥1750 In-stock
50 μg ￥3800 In-stock
100 μg   询价  

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描述

NCAM-1/CD56 protein is an important cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. It interacts with MDK and forms a complex with SLC39A6 and SLC39A10, complexly regulating NCAM-1 phosphorylation. NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is 699 a.a., with molecular weight of 95-115 kDa.
研究背景

NCAM-1/CD56 蛋白作为细胞粘附分子发挥着关键作用，参与神经元-神经元粘附、神经突束颤和神经突生长。它与 MDK 相互作用，并与 SLC39A6、SLC39A10 及其自身形成复合物。正如研究中所观察到的，该复合物复杂地调节 NCAM-1 磷酸化，并促进其在上皮-间质转化过程中整合到粘着斑复合物中。NCAM-1 在细胞粘附和信号传导过程中的广泛参与凸显了其在介导复杂细胞相互作用中的重要性，这对神经元发育以及上皮和间质状态之间的转换至关重要。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

XP_005579710.1 (L20-G718)
基因 ID
蛋白结构
N-term
NCAM-1 (L20-G718)
Accession # XP_005579710.1
His
C-term
同用名
N-CAM-1; NCAM-1; NCAM1; CD56; NCAM; MSK39
分子量

95-115 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液
组分

Supplied as a 0.22μm filtered solution of 50mM Tris, 500mM NaCl, pH 8.0.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (147 KB)

产品使用指南 (1213 KB)

NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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