1. 重组蛋白
  2. Viral Proteins Biotinylated Proteins
  3. Influenza Viruses Proteins
  4. Influenza Virus Neuraminidase
  5. Neuraminidase/NA 蛋白, H5N1 (Biotinylated, HEK293, His)

Neuraminidase/NA 蛋白, H5N1 (Biotinylated, HEK293, His)

目录号: HY-P77556
产品使用指南

神经氨酸酶/NA 蛋白可去除病毒和细胞糖复合物中的末端唾液酸,帮助病毒释放和传播。Neuraminidase/NA 蛋白, H5N1 (Biotinylated, HEK293, His) 是重组的 神经氨酸酶/NA 蛋白,由 HEK293 表达,带有 N-His 标签。Neuraminidase/NA 蛋白, H5N1 (Biotinylated, HEK293, His) 全长 414 个氨基酸,分子量约为 ~55 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Neuraminidase/NA proteins remove terminal sialic acids from viral and cellular glycocomplexes, aiding virus release and spread. Neuraminidase/NA Protein, H5N1 (Biotinylated, HEK293, His) is the recombinant Virus-derived Neuraminidase/NA protein, expressed by HEK293 , with N-His labeled tag. The total length of Neuraminidase/NA Protein, H5N1 (Biotinylated, HEK293, His) is 414 a.a., with molecular weight of ~55 kDa.

研究背景

神经氨酸酶 (NA) 蛋白通过催化去除病毒和细胞糖复合物中的末端唾液酸残基,在病毒动力学中发挥着至关重要的作用。在病毒出芽过程中,NA 从糖基化血凝素 (HA) 上切下末端唾液酸,促进病毒有效释放,并通过进一步去除细胞表面的唾液酸,帮助病毒在循环中传播。这些裂解防止自我聚集并确保子代病毒在细胞之间有效传播,从而防止感染仅限于单轮复制。NA 作为一种受体破坏酶,将末端唾液酸从细胞受体上裂解下来,通过靶向气道上皮细胞粘蛋白上的唾液酸部分,可能促进病毒入侵上呼吸道。它在细胞内运输过程中与脂筏的关联表明它在出芽过程中发挥作用,并且它还可能对出芽发挥独立于脂筏的作用,有助于宿主范围限制、复制和毒力测定。晚期内体/溶酶体运输中的唾液酸酶活性似乎增强了病毒复制。

种属

Virus

表达系统

HEK293

标签

N-His

蛋白编号

Q6Q793 (H36-K449)

基因 ID

/

蛋白结构
N-term
His
H5N1 NA (H36-K449)
Accession # Q6Q793
C-term
同用名
Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His , Biotinylated)
分子量

Approximately 55 kDa

纯度

Greater than 80% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Neuraminidase/NA Protein, H5N1 (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Neuraminidase/NA Protein, H5N1 (Biotinylated, HEK293, His)
目录号:
HY-P77556
需求量: