NGL-1/LRRC4C 蛋白, Mouse (HEK293, His)

NGL-1/LRRC4C protein promotes neurite outgrowth in thalamic neurons, shaping neural circuit architecture. It interacts with NTNG1 and WHRN to modulate neurite outgrowth and synaptic connections. Investigating its mechanisms and downstream effects could provide insights into its role in neural development and circuit formation. NGL-1/LRRC4C Protein, Mouse (HEK293, His) is the recombinant mouse-derived NGL-1/LRRC4C protein, expressed by HEK293 , with C-His labeled tag.

NGL-1/LRRC4C 蛋白似乎在促进丘脑神经元发育中的神经突生长中发挥作用，表明其参与神经元生长和连接的复杂过程。它促进神经突延伸的潜力意味着在塑造神经回路结构中具有关键功能。此外，NGL-1/LRRC4C 与 NTNG1 和 WHRN 相互作用，表明其参与分子相互作用，可以进一步调节神经突生长并影响突触连接的发展。进一步探索 NGL-1/LRRC4C 在促进神经突生长中的具体机制和下游效应及其与 NTNG1 和 WHRN 的相互作用，可以为其在神经发育和回路形成中的作用提供有价值的见解。

Measured by its binding ability in a functional ELISA. Immobilized Mouse NGL-1 at 2 μg/mL (100 μL/well) can bind Human NTNG1(HY-P71176). The KD for this effect is 3.013 nM.

Mouse

HEK293

C-10*His

Q8C031/BAC27884.1 (Q45-K527)

241568  [NCBI]

QTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTK

Approximately 95-115 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.