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  3. Niemann Pick C2/NPC2 蛋白, Rat (HEK293, His)

Niemann Pick C2/NPC2 蛋白, Rat (HEK293, His)

目录号: HY-P74692
COA 产品使用指南

Niemann-Pick C2/NPC2蛋白是NPC2家族的重要成员,在脂质代谢和转运中发挥重要作用,有助于调节细胞内胆固醇稳态和脂质转运。它参与细胞过程凸显了其在维持脂质稳态方面的重要性。Niemann Pick C2/NPC2 蛋白, Rat (HEK293, His) 是重组的 Niemann Pick C2/NPC2 蛋白,由 HEK293 表达,带有 C-His 标签。

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10 μg ¥950 In-stock
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100 μg ¥4400 In-stock
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描述

Niemann-Pick C2/NPC2 protein is an important member of the NPC2 family and plays an important role in lipid metabolism and transport, helping to regulate intracellular cholesterol homeostasis and lipid transport.Its involvement in cellular processes highlights its importance in maintaining lipid homeostasis.Niemann Pick C2/NPC2 Protein, Rat (HEK293, His) is the recombinant rat-derived Niemann Pick C2/NPC2 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

Niemann-Pick C2/NPC2 蛋白是 NPC2 家族的重要成员,在脂质代谢和转运中发挥着重要作用。作为该家族的一部分,NPC2 有助于调节细胞内的胆固醇稳态和脂质运输。它参与细胞过程凸显了其在维持细胞脂质平衡中的重要性。该蛋白属于 NPC2 家族,表明该蛋白家族具有共同的功能特征,可能影响脂质相关途径和细胞功能。NPC2 的研究提供了对脂质转运和代谢的更广泛理解的见解,强调了其与细胞稳态的相关性以及对脂质失调相关疾病的潜在影响。

种属

Rat

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8CHN5 (E20-G149)

基因 ID

/

蛋白结构
N-term
NPC2 (E20-G149)
Accession # Q8CHN5
His
C-term
同用名
NPC intracellular cholesterol transporter 2; Niemann-Pick disease type C2 protein; HE1
氨基酸序列

EPLHFKDCGSKVGVIKEVNVSPCPTQPCQLHKGQSYSVNVTFTSGTQSQNSTALVHGILAGVPVYFPIPEPDGCKCGINCPIQKDKVYSYLNKLPVKSEYPSLKLVVEWKLQDDKKDNLFCWEIPVEIKG

分子量

Approximately 19-22 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Niemann Pick C2/NPC2 Protein, Rat (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Niemann Pick C2/NPC2 Protein, Rat (HEK293, His)
目录号:
HY-P74692
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