1. 重组蛋白
  2. Others
  3. NPR1 蛋白, Human (HEK293, His)

NPR1 蛋白, Human (HEK293, His)

目录号: HY-P703074
COA 产品使用指南 技术支持

NPR1 蛋白是心房钠尿肽 NPPA/ANP 和脑钠尿肽 NPPB/BNP 的受体,在配体结合后启动具有鸟苷酸环化酶活性的信号级联。这些肽是必需的血管活性激素,可调节心血管稳态。NPR1 通过其作为这些利尿钠肽受体的作用,对心血管系统中的血管张力和液体平衡调节有显着贡献。NPR1 蛋白, Human (HEK293, His) 是重组的 NPR1 蛋白,由 HEK293 表达,带有 C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

NPR1 Protein, a receptor for atrial natriuretic peptide NPPA/ANP and brain natriuretic peptide NPPB/BNP, initiates signaling cascades with guanylate cyclase activity upon ligand binding. Essential vasoactive hormones, these peptides regulate cardiovascular homeostasis. NPR1 significantly contributes to vascular tone and fluid balance regulation in the cardiovascular system through its role as a receptor for these natriuretic peptides. NPR1 Protein, Human (HEK293, His) is the recombinant human-derived NPR1 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

NPR1 蛋白是心房钠尿肽 NPPA/ANP 和脑钠尿肽 NPPB/BNP 的受体,这两种重要的血管活性激素在心血管稳态中发挥着关键作用。与这些配体结合后,NPR1 表现出鸟苷酸环化酶活性,启动对维持心血管平衡至关重要的信号级联反应。通过其作为这些利钠肽受体的作用,NPR1 对心血管系统中血管张力和体液平衡的调节发挥着重要作用。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P16066 (G33-E473)

基因 ID

4881

蛋白结构
N-term
NPR1 (G33-E473)
Accession # P16066
His
C-term
同用名
ANP-A; ANPa; Atrionatriuretic peptide receptor A; Guanylate cyclase A; Guanylate cyclase; GUC2A; NPRA
氨基酸序列

GNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLE

分子量

Predicted band size:50.51 kDa; Observed band size: 60-75 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

NPR1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
NPR1 Protein, Human (HEK293, His)
目录号:
HY-P703074
需求量: