OMGP 蛋白, Mouse (HEK293, His)

OMGP protein is a cell adhesion molecule that plays a crucial role in the interactive process necessary for myelination in the central nervous system. It accomplishes this by binding to RTN4R, facilitating the formation and maintenance of myelin sheaths. OMGP Protein, Mouse (HEK293, His) is the recombinant mouse-derived OMGP protein, expressed by HEK293 , with C-His labeled tag.

OMGP 蛋白是一种膜相关蛋白，参与调节轴突生长和神经发育。它与 Nogo 受体相互作用，抑制轴突再生。OMGP 蛋白在神经可塑性中的作用使其成为旨在促进神经系统疾病和损伤的神经再生和功能恢复的治疗干预的潜在目标。

Measured by its ability to inhibit proliferation of SH-SY5Y cells. The ED₅₀ for this effect is 4.59 μg/mL, corresponding to a specific activity is 217.865 units/mg.

Mouse

HEK293

C-6*His

Q63912 (I25-T245)

18377  [NCBI]

ICPLQCTCTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSCDHKQNITYLLKWVMET

Approximately 40-52 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.