PBP1A 蛋白, Mycobacterium tuberculosis

PBP1A (penicillin-binding protein 1A) is involved in cell wall formation and plays a crucial role in the synthesis of cross-linked peptidoglycan from lipid intermediates. The enzyme has a bifunctional structure. The penicillin-insensitive transglycosylase N-terminal domain is responsible for the formation of linear glycan chains, and the penicillin-sensitive transpeptidase C-terminal domain promotes the cross-linking of peptide subunits. PBP1A Protein, Mycobacterium tuberculosis is the recombinant PBP1A protein, expressed by E. coli , with tag free. The total length of PBP1A Protein, Mycobacterium tuberculosis is 430 a.a., .

PBP1A（青霉素结合蛋白 1A）是一种参与细菌细胞壁形成的关键酶，特别是参与从脂质中间体合成交联肽聚糖。该蛋白具有双功能结构，其中青霉素不敏感的转糖基酶 N 端结构域负责形成线性聚糖链，而青霉素敏感的转肽酶 C 端结构域则促进肽亚基的交联。虽然 PBP1A 本身的肽聚糖水解活性有限，但它在抑制 RipA 和 RpfB 的协同肽聚糖水解方面发挥着显着作用。该信息源自参考文献，其中指出 PBP1A 参与细胞壁形成、合成交联肽聚糖，并具有青霉素不敏感的转糖基酶和青霉素敏感的转肽酶活性。

Others

E. coli

Tag Free

P71707 (K391-P820)

887065

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.