2. 重组蛋白
  3. Cytokines and Growth Factors CD Antigens Receptor Proteins Enzymes & Regulators
  4. PDGFs & PDGFRs Platelet CD Proteins Endothelial cell CD Proteins Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. PDGF-R-beta PDGFR
  6. PDGF-R-beta
  7. PDGF R beta 蛋白, Rhesus Macaque (HEK293, Fc)

PDGF R beta 蛋白, Rhesus Macaque (HEK293, Fc)

目录号: HY-P77128
产品使用指南

PDGF R beta 是一种酪氨酸蛋白激酶受体，对胚胎发育起着至关重要的调节作用，监督增殖、存活、分化、趋化和迁移等细胞过程。它在血管发育中尤其重要，可促进周细胞和平滑肌细胞增殖、迁移和招募内皮细胞，在血管形成和维护中发挥重要作用。PDGF R beta 蛋白, Rhesus Macaque (HEK293, Fc) 是重组的 PDGF R β 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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规格 是否有货
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描述

PDGF R beta, a tyrosine-protein kinase receptor, crucially regulates embryonic development, overseeing cell processes like proliferation, survival, differentiation, chemotaxis, and migration. Especially vital in blood vessel development, it facilitates pericyte and smooth muscle cell proliferation, migration, and recruitment to endothelial cells, playing a significant role in blood vessel formation and maintenance. PDGF R beta Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

PDGF R beta 是一种酪氨酸蛋白激酶，作为同二聚体 PDGFB 和 PDGFD 以及由 PDGFA 和 PDGFB 形成的异二聚体的细胞表面受体。该受体在胚胎发育的复杂调节中发挥着至关重要的作用，监督细胞增殖、存活、分化、趋化性和迁移等过程。PDGF R beta 在血管发育中尤其重要，可促进周细胞和平滑肌细胞的增殖、迁移以及向内皮细胞的募集，从而对血管的形成和维护做出重大贡献。
种属

Rhesus Macaque
表达系统

HEK293
标签

C-hFc
蛋白编号

F7BTH1/XP_001107595.1 (L33-F530)
基因 ID
蛋白结构
N-term
PDGF R beta (L33-F530)
Accession # F7BTH1/XP_001107595.1
hFc
C-term
同用名
Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
分子量

Approximately 83.3 kDa.
纯度

Greater than 85% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PDGF R beta Protein, Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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