PDRG1 蛋白, Human (His)

As a component of the PAQosome complex, the PDRG1 protein may play a role in chaperone-mediated protein folding. PAQosome is composed of multiple protein complexes, including PDRG1, and coordinates the biogenesis of multiple protein complexes. PDRG1 Protein, Human (His) is the recombinant human-derived PDRG1 protein, expressed by E. coli , with N-His labeled tag.

PDRG1 蛋白被认为可能在分子伴侣介导的蛋白质折叠中发挥作用。它被确定为 PAQosome 复合物的组成部分，负责多种蛋白质复合物的生物发生。PAQosome 由 R2TP 复合体成员 RUVBL1、RUVBL2、RPAP3 和 PIH1D1，以及 URI 复合体成员 PFDN2、PFDN6、PDRG1、UXT 和 URI1，以及 ASDURF、POLR2E 和 DNAAF10/WDR92 组成。PDRG1 在 PAQosome 复合物中的存在凸显了其在协调各种蛋白质复合物的组装和成熟中的潜在参与，强调了其在与蛋白质折叠和复合物生物发生相关的细胞过程中的重要性。PAQosome 的复杂组成强调需要进一步研究以阐明 PDRG1 在这种动态细胞复合物中的特定功能和分子相互作用。

Human

E. coli

N-6*His

Q9NUG6 (M1-G133)

81572  [NCBI]

MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG

Approximately 12 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 6.5, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.