1. 重组蛋白
  2. Enzymes & Regulators
  3. Oxidoreductases (EC 1)
  4. PRDX1 蛋白, Mouse (His)

PRDX1 蛋白, Mouse (His)

目录号: HY-P73713
COA 产品使用指南

PRDX1 蛋白是一种硫醇特异性过氧化物酶,可催化过氧化氢和有机氢过氧化物还原为水和醇。它在细胞保护免受氧化应激方面的关键作用包括解毒超氧化物和充当过氧化氢介导的信号事件的传感器。PRDX1 蛋白, Mouse (His) 是重组的 PRDX1 蛋白,由 E. coli 表达,带有 C-His 标签。

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规格 价格 是否有货 数量
5 μg ¥800 In-stock
10 μg ¥1350 In-stock
50 μg ¥3800 In-stock
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The PRDX1 protein is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols.Its key role in cellular protection against oxidative stress includes detoxifying superoxide and acting as a sensor of hydrogen peroxide-mediated signaling events.PRDX1 Protein, Mouse (His) is the recombinant mouse-derived PRDX1 protein, expressed by E.coli , with C-His labeled tag.

研究背景

PRDX1 是一种硫醇特异性过氧化物酶,可作为还原过氧化氢和有机氢过氧化物的催化剂,将它们分别转化为水和醇。它在细胞保护免受氧化应激方面的关键作用包括解毒过氧化物并充当过氧化氢介导的信号事件的传感器。此外,PRDX1 可能有助于生长因子和肿瘤坏死因子-α 启动的信号级联,从而控制细胞内 H(2)O(2) 浓度。值得注意的是,PRDX1 表现出减少 GDPD5 中分子内二硫键的能力,从而调节 GDPD5 驱动有丝分裂后运动神经元分化的能力。这些不同的功能强调了 PRDX1 在与氧化还原信号传导和分化相关的细胞过程中的多功能且复杂的调节作用。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Mouse

表达系统

E. coli

标签

C-His

蛋白编号

P35700 (M1-K199)

基因 ID
蛋白结构
N-term
PRDX1 (M1-K199)
Accession # P35700
His
C-term
同用名
Peroxiredoxin-1; OSF-3; PRDX1; Msp23; Paga; Tdpx2
分子量

Approximately 27 kDa

纯度

Greater than 85% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.22 μm filtered solution of PBS, 10% glycerol, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料

PRDX1 Protein, Mouse (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PRDX1 Protein, Mouse (His)
目录号:
HY-P73713
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