PIK3IP1 蛋白, Human (HEK293, His)

PIK3IP1 protein acts as a potent negative regulator of phosphatidylinositol 3-kinase (PI3K) activity in the liver. It crucially modulates the PI3K signaling pathway, exerting inhibitory control over cellular processes influenced by PI3K. PIK3IP1's regulatory function emphasizes its significance in finely tuning intracellular signaling, particularly in hepatic processes where PI3K plays a central role in various cellular functions. PIK3IP1 Protein, Human (HEK293, His) is the recombinant human-derived PIK3IP1 protein, expressed by HEK293 , with C-6*His labeled tag.

PIK3IP1 蛋白作为肝脏中磷脂酰肌醇 3-激酶 (PI3K) 活性的有效负调节因子。通过其调节作用，PIK3IP1 在调节 PI3K 信号通路中发挥着至关重要的作用，对受 PI3K 活性影响的细胞过程发挥抑制性控制。这种调节功能凸显了 PIK3IP1 在微调细胞内信号传导事件中的重要性，特别是在肝脏过程中 PI3K 在各种细胞功能中发挥核心作用。

Human

HEK293

C-6*His

Q96FE7-1 (S22-T168)

113791  [NCBI]

SGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPETTSQALPAFTTEIQEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGT

25-37 KDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.