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  3. PLAU/uPA 蛋白, Cynomolgus (HEK293, His)

PLAU/uPA 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700811
产品使用指南

PLAU,也称为 uPA(尿激酶纤溶酶原激活剂),在对传播特征注释至关重要的保守残基中表现出缺陷。PLAU/uPA 蛋白中的这种缺陷阻止了与该蛋白相关的特定功能特征的传播。PLAU/uPA 蛋白, Cynomolgus (HEK293, His) 是重组的 PLAU/uPA 蛋白,由 HEK293 表达,带有 C-His 标签。PLAU/uPA 蛋白, Cynomolgus (HEK293, His) 全长 410 个氨基酸,分子量为 23-25 kDa (long chain A), 35-40 kDa (cha。

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描述

PLAU, also known as uPA (urokinase plasminogen activator), exhibits defects in conserved residues critical for propagation feature annotation. This defect in the PLAU/uPA protein prevents the propagation of specific functional characteristics associated with this protein. PLAU/uPA Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag. The total length of PLAU/uPA Protein, Cynomolgus (HEK293, His) is 410 a.a., with molecular weight of 23-25 kDa (long chain A), 35-40 kDa (cha.

研究背景

PLAU,也称为 uPA(尿激酶纤溶酶原激活剂),表现出对传播特征注释至关重要的保守残基的缺陷。PLAU/uPA 蛋白的这种缺陷阻碍了与该蛋白相关的特定功能特征的传播。PLAU/uPA 是一种丝氨酸蛋白酶,在纤溶酶原激活系统中发挥作用,在纤维蛋白溶解和细胞外基质重塑的调节中发挥关键作用。它将纤溶酶原转化为纤溶酶,纤溶酶是一种降解纤维蛋白凝块和各种细胞外基质成分的蛋白酶。PLAU/uPA 参与组织重塑、细胞迁移、血管生成和细胞侵袭等过程。PLAU/uPA 蛋白中保守残基的缺乏可能对纤维蛋白溶解调节和细胞外基质动力学产生重大影响,需要进一步研究这种缺陷对蛋白质生物活性的功能影响。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5WND1 (S21-L430)

基因 ID

102135886

蛋白结构
N-term
PLAU (S21-L430)
Accession # A0A2K5WND1
His
C-term
同用名
PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
分子量

23-25 kDa (long chain A), 35-40 kDa (cha

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PLAU/uPA Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PLAU/uPA Protein, Cynomolgus (HEK293, His)
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HY-P700811
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