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  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. PLAU/uPA 蛋白, Human (Biotinylated, HEK293, His-Avi)

PLAU/uPA 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P78195
产品使用指南

uPA 链 A 蛋白是纤溶酶原激活系统的关键参与者,可选择性裂解纤溶酶原,启动纤维蛋白溶解并促进组织重塑。其精确性强调了其在调节蛋白水解活性中的作用,强调了其在导致各种生理过程中纤维蛋白溶解和细胞外基质重塑的级联事件中的重要性。PLAU/uPA 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 PLAU/uPA 蛋白,由 HEK293 表达,带有 C-His, C-Avi 标签。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

uPA chain A Protein, a key player in the plasminogen activation system, selectively cleaves plasminogen, initiating fibrinolysis and contributing to tissue remodeling. Its precision underscores its role in regulating proteolytic activity, emphasizing its significance in the cascade of events leading to fibrinolysis and extracellular matrix remodeling in various physiological processes. PLAU/uPA Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived PLAU/uPA protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

研究背景

uPA 链 A 是纤溶酶原激活系统中的关键角色,在选择性裂解酶原纤溶酶原以生成称为纤溶酶的酶活性形式时发挥着关键作用。这种蛋白水解激活是纤维蛋白溶解的关键步骤,纤溶酶的作用是降解纤维蛋白凝块并有助于组织重塑和修复。uPA 链 A 在裂解纤溶酶原方面的精确性强调了其在调节蛋白水解活性的微妙平衡中的重要性,强调了其在导致纤维蛋白溶解和涉及细胞外基质重塑的其他生理过程的级联事件中作为关键引发剂的作用。

种属

Human

表达系统

HEK293

标签

C-His;C-Avi

蛋白编号

P00749-1 (S21-L431)

基因 ID
蛋白结构
N-term
PLAU (S21-L431)
Accession # P00749-1
His-Avi
C-term
同用名
PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
分子量

24-26 kDa (chain A)&35-38 kDa (chain B) &52-60 kDa (chain A&chain B)

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PLAU/uPA Protein, Human (Biotinylated, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PLAU/uPA Protein, Human (Biotinylated, HEK293, His-Avi)
目录号:
HY-P78195
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