PMP2 蛋白, Human (His)

The PMP2 protein may act as a lipid transporter within Schwann cells, suggesting a role in lipid transport and cellular homeostasis. PMP2 may also bind cholesterol, suggesting involvement in cholesterol-related pathways. PMP2 Protein, Human (His) is the recombinant human-derived PMP2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PMP2 Protein, Human (His) is 132 a.a., with molecular weight of 14-20 kDa.

PMP2 蛋白可能充当雪旺细胞内的脂质转运蛋白，表明其参与脂质转运和细胞稳态的复杂过程。此外，PMP2 可能在结合胆固醇方面发挥作用，表明它可能参与胆固醇相关途径或细胞功能。在结构上，PMP2 作为单体发挥作用，强调其在细胞机器中的独立单元。PMP2 促进脂质转运和胆固醇结合的精确机制，以及其在雪旺细胞生物学中的具体作用，仍然是人们感兴趣的领域，需要进一步探索，以揭示其在脂质稳态背景下的功能意义和分子相互作用。

Human

E. coli

N-6*His

P02689 (M1-V132)

5375  [NCBI]

MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKMKGVVCTRIYEKV

14-20 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Citrate, 10% Trehalose, 100 mM NaCl, 0.05% Tween 80, pH 4.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.