2. 重组蛋白
  3. Enzymes & Regulators
  4. Oxidoreductases (EC 1)
  5. PRDX3 蛋白, Human

PRDX3 蛋白, Human

目录号: HY-P71147
COA 产品使用指南

PRDX3 蛋白是一种硫醇特异性过氧化物酶，通过将过氧化氢和有机氢过氧化物还原为水和醇，在细胞防御中发挥关键作用。它可以解毒过氧化物并与 MAP3K13 配合调节 NF-kappa-B 激活。PRDX3 蛋白, Human 是重组的 PRDX3 蛋白，由 E. coli 表达，不带标签。

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规格 价格 是否有货 数量
10 μg ￥1180 In-stock
50 μg ￥3300 询价
100 μg   询价  

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描述

The PRDX3 protein is a thiol-specific peroxidase that plays a key role in cellular defense by reducing hydrogen peroxide and organic hydroperoxides to water and alcohols. It detoxifies peroxides and cooperates with MAP3K13 to regulate NF-kappa-B activation. PRDX3 Protein, Human is the recombinant human-derived PRDX3 protein, expressed by E. coli , with tag free.
研究背景

PRDX3 是一种硫醇特异性过氧化物酶，在过氧化氢和有机氢过氧化物分别还原为水和醇的过程中充当关键催化剂。这种酶活性在细胞通过解毒过氧化物来防御氧化应激方面发挥着至关重要的作用。除了作为过氧化物酶的作用外，PRDX3 还与 MAP3K13 协同作用，调节细胞质中 NF-kappa-B 的激活。这种多功能蛋白质不仅是细胞防御氧化损伤不可或缺的一部分，而且有助于维持体力，强调其在细胞稳态和应激反应途径中的重要性。
生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
种属

Human
表达系统

E. coli
标签

Tag Free
蛋白编号

P30048-1 (P63-Q256)
基因 ID
蛋白结构
N-term
PRDX3 (P63-Q256)
Accession # P30048-1
C-term
同用名
Thioredoxin-Dependent Peroxide Reductase Mitochondrial; Antioxidant Protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog; PRDX3; AOP1
氨基酸序列

PAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ

分子量

Approximately 25.0 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液
组分

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.
内毒素含量

<1 EU/μg, determined by LAL method.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (208 KB)

产品使用指南 (1213 KB)

PRDX3 Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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