1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. PRKX 蛋白, Human (Sf9, GST)

PRKX 蛋白, Human (Sf9, GST)

目录号: HY-P701761
产品使用指南

PRKX 是一种重要的丝氨酸/苏氨酸激酶,可介导 cAMP 信号传导并磷酸化 CREB、SMAD6 和 PKD1 等靶标。它通过SMAD6磷酸化调节骨髓细胞分化,通过增强肾上皮细胞迁移和肾小管生成促进肾发生,并通过影响内皮细胞增殖和迁移积极促进血管生成。PRKX 蛋白, Human (Sf9, GST) 是重组的 PRKX 蛋白,由 Sf9 insect cells 表达,带有 N-GST 标签。PRKX 蛋白, Human (Sf9, GST) 全长 358 个氨基酸。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

PRKX is an important serine/threonine kinase that mediates cAMP signaling and phosphorylates targets such as CREB, SMAD6, and PKD1. It regulates myeloid cell differentiation through SMAD6 phosphorylation, promotes nephrogenesis by enhancing renal epithelial cell migration and tubulogenesis, and actively promotes angiogenesis by affecting endothelial cell proliferation and migration. PRKX Protein, Human (Sf9, GST) is the recombinant human-derived PRKX protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PRKX Protein, Human (Sf9, GST) is 358 a.a., .

研究背景

PRKX 是一种丝氨酸/苏氨酸蛋白激酶,作为细胞内 cAMP 信号传导的关键介质。其功能植根于磷酸化下游靶标,可能包括 CREB、SMAD6 和 PKD1,从而协调细胞分化和上皮形态发生中的多种作用。PRKX 通过 SMAD6 磷酸化在调节骨髓细胞分化中发挥关键作用,并通过刺激肾上皮细胞的迁移和肾小管生成来促进肾发生。此外,PRKX 积极参与血管生成,通过促进内皮细胞增殖、迁移和血管样结构的形成来发挥其影响。PRKX 的多方面功能强调了其在协调发育和组织形态发生所必需的复杂细胞过程中的重要性。

种属

Human

表达系统

Sf9 insect cells

标签

N-GST

蛋白编号

P51817 (M1-F358)

基因 ID

5613

蛋白结构
N-term
GST
PRKX (M1-F358)
Accession # P51817
C-term
同用名
PRKX; cAMP-dependent protein kinase catalytic subunit PRKX; PrKX; Protein kinase X; Protein kinase X-linked; Serine/threonine-protein kinase PRKX; Protein kinase PKX1
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PRKX Protein, Human (Sf9, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
PRKX Protein, Human (Sf9, GST)
目录号:
HY-P701761
需求量: