RBKS 蛋白, Human (His)

RBKS protein plays a central role in cellular metabolism by catalyzing the phosphorylation of ribose at the O-5 site, a process that is dependent on ATP and magnesium. This enzymatic activity leads to the formation of D-ribose-5-phosphate, a versatile precursor that can be used in various biosynthetic pathways. RBKS Protein, Human (His) is the recombinant human-derived RBKS protein, expressed by E. coli , with N-6*His labeled tag.

RBKS 蛋白通过催化 O-5 位点核糖的磷酸化（这一反应需要 ATP 和镁）在细胞代谢中发挥着至关重要的作用。这种酶活性导致 D-核糖-5-磷酸的形成，这是一种重要的中间体，可用于合成核苷酸，包括嘌呤和嘧啶，以及组氨酸和色氨酸。此外，D-核糖-5-磷酸作为戊糖磷酸途径的关键成分，有助于还原当量和核苷酸前体的生成。RBKS 在引导 5-磷酸核糖进入各种生物合成途径方面的多功能性强调了其在协调核苷酸和能量代谢所必需的细胞过程中的重要性。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。

Data is not available.

Human

E. coli

N-6*His

Q9H477-1 (M1-F322)

64080  [NCBI]

MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLPLTLF

Approximately 37 kDa

• 
  Greater than 85 % as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of sterile 50mM Tris-HCL, 300mM NaCl, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween 80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.