S100A14 蛋白, Human (His, solution)

The S100A14 protein, encoded by a gene on chromosome 1, is a member of the S100 protein family with calcium-binding ability. It shows decreased levels in cancerous tissue, suggesting a potential tumor suppressor role and association with metastasis. S100A14 exhibits biased expression in the esophagus (RPKM 798.1), skin (RPKM 171.2), and other tissues, indicating its potential significance in these contexts. S100A14 Protein, Human (His, solution) is the recombinant human-derived S100A14 protein, expressed by E. coli , with N-His labeled tag. The total length of S100A14 Protein, Human (His, solution) is 103 a.a., with molecular weight of ~12 kDa.

S100A14 蛋白是 S100 蛋白家族的一员，其特征在于其 EF 手基序和钙结合能力，由位于 1 号染色体上的 S100 基因簇中的该基因编码。值得注意的是，已观察到该蛋白的水平下降在癌组织中，表明其作为肿瘤抑制因子的潜在作用及其与转移的相关性（PMID：19956863、19351828）。此外，表达分析揭示了 S100A14 在食道 (RPKM 798.1)、皮肤 (RPKM 171.2) 和其他几种组织中的偏向表达，突出了其在这些情况下的潜在意义。

Human

E. coli

N-His

NP_065723.1 (G2-H104)

57402

GQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERPVRGH

Approximately 12 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4, 20% Glycerol.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.