S100A2 蛋白, Human (HEK293, hFc)

Protein S100-A2 (S100A2) is a member of the S100 family. S100A2 is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes. S100A2 may function as calcium sensor and modulator, contributing to cellular calcium signaling or function by interacting with other proteins and indirectly play a role in many physiological processes. S100A2 may also play a role in suppressing tumor cell growth. S100A2 Protein, Human (HEK293, hFc) is the recombinant human-derived S100A2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of S100A2 Protein, Human (HEK293, hFc) is 97 a.a., with molecular weight of ~40 kDa.

S100- A2 蛋白 (S100A2) 是 S100 蛋白家族的一员，含有 2 个 EF-hand 钙结合基序。S100A2 定位于多种细胞的细胞质和/或细胞核中，参与许多细胞过程的调节，如细胞周期的进展和分化。S100A2 可能作为钙传感器和调节剂参与细胞钙信号传导，或通过与其他蛋白 (如含 TPR 蛋白) 相互作用产生功能，并间接参与许多生理过程。S100A2 也可能在抑制肿瘤细胞生长中发挥作用，染色体重排和 S100A2 表达的改变与乳腺癌有关^[1][2]。

Human

HEK293

N-hFc

NP_005969.1 (M2-P98)

6273  [NCBI]

MCSSLEQALAVLVTTFHKYSCQEGDKFKLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEYAVFLALITVMCNDFFQGCPDRP

Approximately 40 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5 or 50 mM Tris, 10 mM Nacl, 100 Glyane, PH 7.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.