2. 重组蛋白
  3. Viral Proteins
  4. SARS-CoV-2 Proteins
  5. SARS-CoV-2 Nucleocapsid Proteins
  6. SARS-CoV-2 N Protein (NP)
  7. SARS-CoV-2 Nucleocapsid 蛋白 (Omicron, B.1.1.529, His)

SARS-CoV-2 Nucleocapsid 蛋白 (Omicron, B.1.1.529, His)

目录号: HY-P74443
COA 产品使用指南

Nucleoprotein/NP 蛋白 对于病毒复制和转录至关重要。Nucleoprotein/NP 蛋白 与病毒 RNA 结合，形成基因组复制所需的核糖核蛋白复合物。Nucleoprotein/NP 蛋白 促进 NLRP3 炎症小体激活来诱导过度炎症。SARS-CoV-2 Nucleocapsid 蛋白 (Omicron, B.1.1.529, His) 是重组的 SARS-CoV-2 核衣壳蛋白，由 E. coli 表达，带有 N-His 标签。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 μg ￥1560 In-stock
50 μg ￥4250 In-stock
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Nucleoprotein/NP Protein is essential for viral replication and transcription. Nucleoprotein/NP Protein binds to viral RNA to form a ribonucleoprotein complex required for genome replication. Nucleoprotein/NP Protein promotes NLRP3 inflammasome activation to induce excessive inflammation. SARS-CoV-2 Nucleocapsid Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 Nucleocapsid protein, expressed by E. coli , with N-His labeled tag.
研究背景

Nucleoprotein/NP Protein 对于病毒复制和转录至关重要。Nucleoprotein/NP Protein 与病毒 RNA 结合，形成基因组复制所需的核糖核蛋白复合物，Nucleoprotein/NP Protein诱导强抗体（Ab） 和 T 细胞反应，调节先天免疫和适应性免疫[1][3]。
Nucleoprotein/NP Protein 通过分泌到细胞外空间起作用，在那里它与宿主趋化因子竞争以与宿主糖胺聚糖（GAG） 结合[2]。
Nucleoprotein/NP Protein 通过促进 NLRP3 炎症小体激活来诱导过度炎症，这在 COVID 肺损伤中发挥作用[4]。
种属

Virus
表达系统

E. coli
标签

N-His
蛋白编号

YP_009724397 (M1-A419, with mutations P13L, ERS31-33 deletion, R203K, G204R)
基因 ID

43740575  [NCBI]
蛋白结构
N-term
His
Nucleocapsid (M1-A419, with mutations P13L, ERS31-33 deletion, R203K, G204R)
Accession # YP_009724397
C-term
同用名
N Protein; Nucleocapsid
氨基酸序列

MSDNGPQNQRNALRITFGGPSDSTGSNQNGGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSKRTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA

分子量

Approximately 46.31 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of 50 mM PB, 500mM NaCl, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (147 KB)

产品使用指南 (1213 KB)

SARS-CoV-2 Nucleocapsid Protein (Omicron, B.1.1.529, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
SARS-CoV-2 Nucleocapsid Protein (Omicron, B.1.1.529, His)
目录号：
HY-P74443
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z