SARS-CoV Plpro/papain-like protease 蛋白 (His)

SARS CoV ORF1ab polyprotein (PP1ab) is a 7073 residues long polyprotein which further produces 5 non-structural proteins (NSPs) after processing through virally encoded proteases (NSP12-NSP16).All these 5 proteins are mainly involved in viral replication, assembly, and immune response modulation.SARS-CoV Plpro/papain-like protease Protein (His) is the recombinant Virus-derived SARS-CoV Plpro/papain-like protease protein, expressed by E.coli , with C-His labeled tag.

SARS CoV ORF1ab 多蛋白 (PP1ab) 是一个 7073 个残基长的多蛋白，通过病毒编码的蛋白酶加工后产生 5 种非结构蛋白 (NSPs, NSP12-NSP16)。这 5 种蛋白主要参与病毒的复制、组装和免疫应答调节。多蛋白降解是由主蛋白酶 (Mpro) 和木瓜蛋白酶样蛋白酶 (PLpro) 介导的，因此 PP1ab 被加工成形成病毒复制和转录复合体的单个 NSPs，病毒 RNA 转录和复制的功能是由 PP1ab 中存在的特定 RNA 依赖 RNA 聚合酶 (RdRp) 区域完成的^[1][2]。

Virus

E. coli

C-His

AAX16193 (E1541-Y1859)

/

Approximately 36.91 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as 0.22 μm filtered solution in 50 mM Tris, 0.1% Tween, 150 mM NaCl, pH 9.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.