SCGB1A1 蛋白, Rat (His)

SCGB1A1 Protein demonstrates diverse binding abilities, interacting with phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB), and, to a lesser extent, progesterone.It acts as a robust phospholipase A2 inhibitor, forming an antiparallel homodimer linked by disulfide bonds.Although there is controversy regarding its interaction with LMBR1L, additional research is necessary for clarification.SCGB1A1 Protein, Rat (His) is the recombinant rat-derived SCGB1A1 protein, expressed by E.coli , with N-6*His labeled tag.

SCGB1A1 蛋白表现出多种结合能力，包括磷脂酰胆碱、磷脂酰肌醇、多氯联苯 (PCB) 和较小程度的黄体酮。它是磷脂酶 A2 的有效抑制剂。在结构上，它形成二硫键连接的反向平行同二聚体。虽然围绕其与 LMBR1L 的相互作用存在一些争议，但需要进一步研究来澄清这一方面。

Measured by the ability of the immobilized protein to affect the adhesion of the A549 human lung carcinoma cells in the presence of Fibronectin. The ED₅₀ for this effect is 3.142 μg/mL, corresponding to a specific activity is 318.27 units/mg.

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  Measured by the ability of the immobilized protein to affect the adhesion of the A549 human lung carcinoma cells in the presence of Fibronectin. The ED₅₀ for this effect is 3.142 μg/mL, corresponding to a specific activity is 318.27 units/mg.

Rat

E. coli

N-6*His

P17559 (S20-V96)

25575  [NCBI]

SSDICPGFLQVLEALLLGSESNYEAALKPFNPASDLQNAGTQLKRLVDTLPQETRINIVKLTEKILTSPLCEQDLRV

Approximately 10 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.