Semaphorin-3A/SEMA3A 蛋白, Rat (His)

Semaphorin-3A/SEMA3A protein plays a potentially crucial role in directing axon growth by creating molecular boundaries that guide the formation of specific nerve tracts. Its binding to neuropilin is implicated in olfactory system development and neuronal regulation of puberty. SEMA3A's interaction with PLXND1 underscores its significance in axon guidance and neural development. Semaphorin-3A/SEMA3A Protein, Rat (His) is the recombinant rat-derived Semaphorin-3A/SEMA3A protein, expressed by E. coli , with N-6*His labeled tag. The total length of Semaphorin-3A/SEMA3A Protein, Rat (His) is 752 a.a., with molecular weight of ~90.6 kDa.

Semaphorin-3A/SEMA3A 蛋白通过创建为特定神经束的形成提供指令的分子边界，对于引导轴突向其预期目标生长可能至关重要。它与神经毡蛋白结合，参与嗅觉系统的发育和青春期的神经元调节。此外，SEMA3A 与 PLXND1 相互作用，进一步强调了其在轴突引导和神经发育中的重要性。

Rat

E. coli

N-6*His

Q63548 (N21-V772)

29751  [NCBI]

NYANGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFNLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEVGHHPEDNIFKLQDSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPRFISAHLIPESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNSKDPKNPIVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPINNRPIMIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSVPKETWHDLEEVLLEEMTVFREPTTISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSSCSRYFPTAKRRTRRQDIRNGDPLTHCSDLQHHDNHHGHSLEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEDRKEEIRVGDHIIRTEQGLLLRSLQKKDSGNYLCHAVEHGFMQTLLKVTLEVIDTEHLEELLHKDDDGDGSKTKEMSSSMTPSQKVWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPGHSQGSSNKWKHMQESKKGRNRRTHEFERAPRSV

Approximately 90.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4 or10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.