2. 重组蛋白
  3. CD Antigens Receptor Proteins Biotinylated Proteins
  4. Macrophage CD Proteins Dendritic Cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. SIRP beta 1/CD172b Immunoglobulin-like Cell Adhesion Molecules
  6. SIRP beta 1/CD172b
  7. SIRP Beta 1 蛋白, Human (isoform 3, HEK293, His-Avi)

SIRP Beta 1 蛋白, Human (isoform 3, HEK293, His-Avi)

目录号: HY-P77838
产品使用指南

SIRP Beta 1 蛋白是一种免疫球蛋白样细胞表面受体，对受体酪氨酸激酶偶联信号传导过程起到至关重要的负调节作用。它调节细胞对细胞粘附、生长因子或胰岛素等刺激的反应，有助于维持细胞稳态并微调与受体酪氨酸激酶相关的信号通路。SIRP Beta 1 蛋白, Human (isoform 3, HEK293, His-Avi) 是重组的 SIRP Beta 1 蛋白，由 HEK293 表达，带有 C-Avi, C-His 标签。SIRP Beta 1 蛋白, Human (isoform 3, HEK293, His-Avi) 全长 342 个氨基酸，分子量为 60-70 kDa。

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描述

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, crucially negatively regulates receptor tyrosine kinase-coupled signaling processes. It modulates cellular responses to stimuli like cell adhesion, growth factors, or insulin, contributing to maintaining cellular homeostasis and finely tuning signaling pathways associated with receptor tyrosine kinases. SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is the recombinant human-derived SIRP Beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is 342 a.a., with molecular weight of 60-70 kDa.
研究背景

SIRP Beta 1 蛋白是一种免疫球蛋白样细胞表面受体，在负向调节受体酪氨酸激酶偶联信号传导过程中发挥着至关重要的作用。该受体调节各种刺激诱导的细胞反应，包括细胞粘附、生长因子或胰岛素。通过其调节功能，SIRP Beta 1 有助于维持细胞稳态并微调与受体酪氨酸激酶相关的信号通路的激活。
种属

Human
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

Q5TFQ8 (E30-L371)
基因 ID
蛋白结构
N-term
SIRP Beta 1 (E30-L371)
Accession # Q5TFQ8
His-Avi
C-term
同用名
SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a
分子量

60-70 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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