SLC29A1 蛋白, Human (Sf9, His, MBP, FLAG)

The SLC29A1 protein is an important uniporter that actively promotes the transport of nucleosides and nucleobases and maintains cellular homeostasis of essential compounds. As a Na(+)-independent transporter, SLC29A1 efficiently transports a series of nucleosides and nucleobases, including adenosine, guanosine, inosine, uridine, thymidine, cytidine, hypoxanthine, adenine, guanine, Thymine and uracil. SLC29A1 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC29A1 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC29A1 Protein, Human (Sf9, His, MBP, FLAG) is 455 a.a., .

SLC29A1 是一种关键的单向转运蛋白，它对核苷和核碱基的促进转运有着复杂的贡献，在维持这些必需化合物的细胞稳态中发挥着至关重要的作用。作为 Na(+) 独立转运蛋白，SLC29A1 积极参与一系列核苷的转运，包括腺苷、鸟苷、肌苷、尿苷、胸苷和胞苷。此外，它还能有效转运嘌呤核碱基（次黄嘌呤、腺嘌呤、鸟嘌呤）和嘧啶核碱基（胸腺嘧啶、尿嘧啶）。这种多功能转运蛋白有助于介导基底外侧核苷摄取到支持细胞中，从而调节睾丸中核苷跨血睾屏障的转运。值得注意的是，SLC29A1 在调节棕色脂肪细胞组织 (BAT) 中的肌苷水平方面发挥着关键作用，从而影响 BAT 依赖性能量消耗。广泛的底物特异性和组织特异性功能凸显了 SLC29A1 在细胞核苷转运和代谢过程中的重要性。

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

Q99808 (T2-V456)

2030

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.