SNTG1 蛋白, Human (Myc, His)

SNTG1 acts as an adapter protein that binds and potentially organizes various proteins, serving as a link between the receptor and the actin cytoskeleton or dystrophin glycoprotein complex. It may modulate the subcellular distribution of diacylglycerol kinase-zeta and contribute to the rapid inactivation of diacylglycerol upon receptor activation. SNTG1 Protein, Human (Myc, His) is the recombinant human-derived SNTG1 protein, expressed by E. coli , with N-His, C-Myc labeled tag.

SNTG1 作为衔接蛋白发挥作用，能够结合并可能组织不同蛋白质的亚细胞定位，可能充当各种受体与肌动蛋白细胞骨架以及肌营养不良蛋白糖蛋白复合物之间的联系。它可能在调节二酰甘油激酶-zeta 的亚细胞分布中发挥作用，以促进受体激活后二酰甘油迅速失活。值得注意的是，与同工型 2 相比，SNTG1 的同工型 1 与肌营养不良蛋白 DMD 及其相关对应物 DTNA 和 DTNB 相互作用。此外，SNTG1 与 DGKZ 形成相互作用，表明其参与调节关键信号分子和结构成分的细胞动力学。

Human

E. coli

N-His;C-Myc

Q9NSN8-1 (M1-T517)

54212  [NCBI]

MDFRTACEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPGTDLSRQNAFQVIAVDGVCTGIIQCLSAEDCVDWLQAIATNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQDPLQDRVYSPTFLALRGSCLYKFLAPPVTTWDWTRAEKTFSVYEIMCKILKDSDLLDRRKQCFTVQSESGEDLYFSVELESDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFICFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQATASTAASSATTSKAKYTT

Approximately 63.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.