1. 重组蛋白
  2. Enzymes & Regulators
  3. Oxidoreductases (EC 1)
  4. SOD2/Mn-SOD 蛋白, Human

SOD2/Mn-SOD 蛋白是细胞防御中的关键酶,可中和超氧阴离子自由基并保护细胞免受氧化应激。SOD2 作为一种含锰超氧化物歧化酶,在分解这些自由基方面发挥着关键作用,对于维持细胞稳态和保护生物系统免受活性氧积累造成的潜在损害至关重要。SOD2/Mn-SOD 蛋白, Human 是重组的 SOD2/Mn-SOD 蛋白,由 E. coli 表达,不带标签。SOD2/Mn-SOD 蛋白, Human 全长 198 个氨基酸,分子量约为 ~25 kDa。

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描述

SOD2/Mn-SOD protein is a key enzyme in cellular defense that neutralizes superoxide anion radicals and protects cells from oxidative stress. SOD2, as a manganese-containing superoxide dismutase, plays a key role in breaking down these free radicals and is essential for maintaining cellular homeostasis and protecting biological systems from potential damage caused by the accumulation of reactive oxygen species. SOD2/Mn-SOD Protein, Human is the recombinant human-derived SOD2/Mn-SOD protein, expressed by E. coli , with tag free. The total length of SOD2/Mn-SOD Protein, Human is 198 a.a., with molecular weight of ~25 kDa.

研究背景

SOD2/Mn-SOD 蛋白是细胞防御中的关键酶,可有效中和超氧阴离子自由基,超氧阴离子自由基是细胞内自然产生的,可能对生物系统有毒。SOD2 作为一种含锰超氧化物歧化酶,在分解这些自由基方面发挥着关键作用,从而保护细胞免受氧化应激的有害影响。SOD2 的酶活性对于维持细胞稳态和保护生物系统免受活性氧积累造成的潜在损害至关重要,凸显了其在细胞健康和恢复力方面的重要性。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

P04179 (K25-K222)

基因 ID
蛋白结构
N-term
SOD2 (K25-K222)
Accession # P04179
C-term
同用名
Superoxide Dismutase [Mn] Mitochondrial; SOD2
分子量

Approximately 25 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

SOD2/Mn-SOD Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SOD2/Mn-SOD Protein, Human
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