SPG21 蛋白, Human (sf9, His)

The SPG21 protein may act as a negative regulator in CD4-dependent T cell activation, suggesting its role in regulating immune responses. Its interaction with CD4 suggests a molecular link affecting CD4-mediated T cell activation pathways. SPG21 Protein, Human (sf9, His) is the recombinant human-derived SPG21 protein, expressed by Sf9 insect cells , with N-His labeled tag.

SPG21 蛋白被认为可能作为 CD4 依赖性 T 细胞激活的负调节因子，表明其参与调节免疫反应。它与 CD4 相互作用，表明可能影响 CD4 介导的 T 细胞激活途径的分子关联。此外，SPG21 与 ALDH16A1 相互作用，表明其可能参与与乙醛脱氢酶家族相关的细胞过程。SPG21 在 T 细胞激活中的调节作用及其与 ALDH16A1 相互作用的具体机制仍然是人们感兴趣的领域，突显了其在免疫调节和细胞代谢中的潜在重要性。

Human

Sf9 insect cells

N-6*His

Q9NZD8-1 (M1-Q308)

51324  [NCBI]

MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ

Approximately 35 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 150 mM NaCl, pH 8.0, 50% Glycerol.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.