SPINK1 蛋白, Human (HEK293, His)

The SPINK1 protein is a serine protease inhibitor that significantly inhibits trypsin, especially in the pancreas, preventing premature activation of the zymogen. This critical role maintains the integrity of pancreatic cellular processes. SPINK1 Protein, Human (HEK293, His) is the recombinant human-derived SPINK1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SPINK1 Protein, Human (HEK293, His) is 56 a.a., with molecular weight of 12-16 kDa.

SPINK1 是一种丝氨酸蛋白酶抑制剂，具有显着的抗胰蛋白酶活性，特别是在胰腺中，它在防止胰蛋白酶催化的酶原过早激活方面发挥着关键作用。这种保护功能有助于维持胰腺内细胞过程的完整性。此外，SPINK1 还参与男性生殖道，与精子头结合，对精子容量产生影响。值得注意的是，SPINK1 通过抑制钙吸收和一氧化氮 (NO) 产生来实现这种调节，在不同的生理环境中展示其多样化的调节功能。

Human

HEK293

C-6*His

P00995 (D24-C79)

6690  [NCBI]

DSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC

12-16 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 500 mM NaCl, 5% Trehalose, 5% Mannitol, 0.02% Tween 80, pH 9.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.