SPINK1 蛋白, Mouse (P.pastoris, His)

SPINK1 is a serine protease inhibitor that significantly inhibits trypsin, especially in the pancreas, preventing premature activation of the zymogen. In the male reproductive tract, SPINK1 binds to sperm heads and regulates sperm volume by inhibiting calcium absorption and nitrogen oxide (NO) production. SPINK1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived SPINK1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of SPINK1 Protein, Mouse (P.pastoris, His) is 57 a.a., with molecular weight of 10 kDa.

SPINK1 是一种丝氨酸蛋白酶抑制剂，具有抗胰蛋白酶作用，对胰蛋白酶具有抑制活性。SPINK1 在胰腺中尤其重要，它是一种保护因子，可防止胰蛋白酶催化的酶原过早激活。除了在胰腺中的作用之外，SPINK1 在男性生殖道中还发挥着独特的功能，它与精子头部结合。在这种情况下，它通过抑制钙的吸收和氮氧化物（NO）的产生来调节精子的容量。这些不同的作用凸显了 SPINK1 在调节蛋白水解活性以及促进胰腺和男性生殖过程中的保护机制方面的重要性。

Mouse

P. pastoris

N-6*His

P09036 (A24-C80)

20730

10 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.