SRFBP1 蛋白, Human (sf9, His-GST)

The SRFBP1 protein is a potential regulator of multiple cellular processes and is involved in aging-associated transcriptional activation of cardiac genes and the biosynthesis/processing of SLC2A4 in adipocytes. Its multifaceted effects extend into metabolic pathways, involving interactions with SRF and formation of complexes with SRF cofactors ARID2, MYOCD, and NKX2-5, highlighting its role in transcriptional regulation. SRFBP1 Protein, Human (sf9, His-GST) is the recombinant human-derived SRFBP1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SRFBP1 Protein, Human (sf9, His-GST) is 429 a.a., with molecular weight of ~69 kDa.

SRFBP1 蛋白作为多种细胞过程中的潜在调节剂出现，对与衰老相关的心脏基因转录激活具有影响。此外，它可能在脂肪细胞中 SLC2A4 的生物合成和/或加工中发挥作用，表明其在代谢途径中的多方面参与。与转录因子 SRF 的相互作用，以及与 SRF 辅因子 ARID2、MYOCD 和 NKX2-5 形成复合物，凸显了 SRFBP1 在转录调节中的作用。此外，它与 SLC2A4 N 末端的相互作用表明它在调节葡萄糖转运过程中具有潜在作用。揭示 SRFBP1 功能的具体机制可以为了解其在心脏衰老、代谢调节和转录控制中的作用提供有价值的见解，从而为更全面地了解其细胞影响铺平道路。

Human

Sf9 insect cells

N-His;N-GST

Q8NEF9 (M1-D429)

153443  [NCBI]

Approximately 69 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% Glycerol, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.