1. 重组蛋白
  2. Enzymes & Regulators
  3. Serine/Threonine Kinase Proteins
  4. SRSF Protein Kinase 3
  5. SRPK3 蛋白, Human (sf9, GST)

SRPK3 蛋白, Human (sf9, GST)

目录号: HY-P76659
产品使用指南

SRPK3 蛋白通过磷酸化 RS 结构域中的底物来精确调节细胞过程。体外研究揭示了 SRPK3 对 SRSF1 和 LBR 等关键靶标的活性,强调了其在正常肌肉发育中不可或缺的作用。SRPK3 的重要性不仅限于分子相互作用,还强调其在协调肌肉成熟的复杂生物途径中不可或缺的作用。SRPK3 蛋白, Human (sf9, GST) 是重组的 SRPK3 蛋白,由 Sf9 insect cells 表达,带有 GST 标签。

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描述

SRPK3 Protein precisely modulates cellular processes by phosphorylating substrates in RS domains. In vitro studies reveal SRPK3's activity on key targets, including SRSF1 and LBR, underscoring its indispensable role in normal muscle development. SRPK3's significance extends beyond molecular interactions, emphasizing its integral part in orchestrating intricate biological pathways for muscle maturation. SRPK3 Protein, Human (sf9, GST) is the recombinant human-derived SRPK3 protein, expressed by Sf9 insect cells , with GST labeled tag.

研究背景

SRPK3 是一种富含丝氨酸/精氨酸的蛋白质特异性激酶,通过选择性磷酸化富含精氨酸/丝氨酸二肽区域(称为 RS 结构域)内丝氨酸残基的底物来复杂地调节细胞过程。体外研究强调了 SRPK3 对 SR 剪接因子 SRSF1 和核纤层蛋白 B 受体 (LBR) 等关键靶点的磷酸化活性。SRPK3 的重要性超越了分子相互作用,因为它被证明对于正常肌肉发育是不可或缺的,强调了它在控制肌肉成熟的生物途径的复杂编排中的不可或缺的作用。

种属

Human

表达系统

Sf9 insect cells

标签

GST

蛋白编号

Q9UPE1-4/NP_001164231.1 (M1-P566)

基因 ID
蛋白结构
N-term
C-term
同用名
SRSF protein kinase 3; MSSK-1; Serine/threonine-protein kinase 23; MSSK1; STK23
分子量

Approximately 100 kDa

纯度

Greater than 80% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

SRPK3 Protein, Human (sf9, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
SRPK3 Protein, Human (sf9, GST)
目录号:
HY-P76659
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