Synaptotagmin VI 蛋白, Human (N-His)

Ptk7 Protein is a receptor that is involved in various cellular processes, including cell proliferation and migration. It plays a crucial role in regulating embryonic development and tissue homeostasis. Dysregulation of Ptk7 Protein has been associated with various diseases, including cancer and developmental disorders. Targeting Ptk7 Protein may offer potential therapeutic interventions in these conditions by inhibiting cell proliferation and migration, and promoting tissue homeostasis. Synaptotagmin VI Protein, Human (N-His) is the recombinant human-derived Synaptotagmin VI protein, expressed by E. coli, with N-His labeled tag. The total length of Synaptotagmin VI Protein, Human (N-His) is 151 a.a., with molecular weight of ~19 kDa.

突触结合蛋白VI蛋白是突触结合蛋白家族的成员，具有包含跨膜结构域和由2个C2结构域组成的细胞质区域的共同结构域结构。这些蛋白质在突触小泡的钙依赖性胞吐作用中发挥着至关重要的作用。具体来说，突触结合蛋白 VI 是顶体胞吐作用中涉及的分泌机制的重要组成部分。该基因表现出选择性剪接的转录变体。此外，它还表明在特定组织中存在偏向表达，包括大脑 (RPKM 2.6)、肾脏 (RPKM 0.8) 和 6 个其他组织。

Human

E. coli

N-His

NP_995320 (V275-L425)

148281

VDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGNPRL

Approximately 19 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.