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  3. Syndecan-4 蛋白, Human (HEK293, His)

Syndecan-4 蛋白, Human (HEK293, His)

目录号: HY-P73623
COA 产品使用指南

研究证明Syndecan-4蛋白是一种细胞表面蛋白聚糖,与SDCBP和PDCD6IP配合在调节外泌体生物发生中发挥关键作用。Syndecan-4 作为同二聚体发挥作用,并通过其细胞质结构域与各种细胞内伙伴相互作用。Syndecan-4 蛋白, Human (HEK293, His) 是重组的 Syndecan-4 蛋白,由 HEK293 表达,带有 C-His 标签。

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规格 价格 是否有货 数量
50 μg ¥3800 In-stock
100 μg   询价  

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描述

Studies have proven that Syndecan-4 protein is a cell surface proteoglycan that cooperates with SDCBP and PDCD6IP to play a key role in regulating exosome biogenesis. Syndecan-4 functions as a homodimer and interacts with various intracellular partners through its cytoplasmic domain. Syndecan-4 Protein, Human (HEK293, His) is the recombinant human-derived Syndecan-4 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

Syndecan-4 是一种细胞表面蛋白聚糖,与 SDCBP 和 PDCD6IP 合作,成为外泌体生物发生的关键调节因子。它形成同二聚体并与各种蛋白质相互作用,包括通过其胞质结构域的 GIPC 和 NUDT16L1。Syndecan-4 进一步与 CDCP1 和 SDCBP 相互作用,强调其参与多种细胞过程和信号传导途径。Syndecan-4 与这些相互作用伙伴之间复杂的相互作用强调了其在细胞表面的多功能作用,表明对外泌体动力学和其他细胞活动的潜在贡献。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P31431-1 (E19-E145)

基因 ID
蛋白结构
N-term
Syndecan-4 (E19-E145)
Accession # P31431-1
His
C-term
同用名
Ryudocan core protein; SDC 4; SYND 4; SYND4; syndecan 4
分子量

Approximately 15.3 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Syndecan-4 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Syndecan-4 Protein, Human (HEK293, His)
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HY-P73623
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