Syndecan-4 蛋白, Human (HEK293, His)

Studies have proven that Syndecan-4 protein is a cell surface proteoglycan that cooperates with SDCBP and PDCD6IP to play a key role in regulating exosome biogenesis. Syndecan-4 functions as a homodimer and interacts with various intracellular partners through its cytoplasmic domain. Syndecan-4 Protein, Human (HEK293, His) is the recombinant human-derived Syndecan-4 protein, expressed by HEK293 , with C-His labeled tag.

Syndecan-4 是一种细胞表面蛋白聚糖，与 SDCBP 和 PDCD6IP 合作，成为外泌体生物发生的关键调节因子。它形成同二聚体并与各种蛋白质相互作用，包括通过其胞质结构域的 GIPC 和 NUDT16L1。Syndecan-4 进一步与 CDCP1 和 SDCBP 相互作用，强调其参与多种细胞过程和信号传导途径。Syndecan-4 与这些相互作用伙伴之间复杂的相互作用强调了其在细胞表面的多功能作用，表明对外泌体动力学和其他细胞活动的潜在贡献。

Human

HEK293

C-His

P31431-1 (E19-E145)

6385  [NCBI]

Approximately 15.3 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.