1. Gene
  2. SDC4 - syndecan 4 Gene

SDC4 - syndecan 4 Gene

中文名称:联癸烷 4

种属: Homo sapiens

同用名: SYND4

基因 ID: 6385 | 基因类型: protein coding

关于 SDC4

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,325,288-45,348,424 (from NCBI)

This gene has 1 transcript (splice variant), 197 orthologues, 3 paralogues and is associated with 48 phenotypes. Broad expression in liver (RPKM 189.5), lung (RPKM 100.6) and 23 other tissues.

功能概要

由该基因编码的蛋白质是一种跨膜 (I 型) 硫酸乙酰肝素蛋白多糖,在细胞内信号传导中起着受体的作用。编码的蛋白质被发现为同源二聚体,并且是聚糖蛋白聚糖家族的成员。该基因位于 20 号染色体上,而假基因位于 22 号染色体上。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

SDC4 基因产物(1)

mRNA Protein Name
NM_002999.4 NP_002990.2 syndecan-4 precursor

SDC4 蛋白结构

Syndecan

Syndecan: Syndecan domain (138 - 196)

  • 0
  • 100
  • 198 a.a.
蛋白主名 其他名称

syndecan-4

amphiglycan

重组 SDC4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73623 Syndecan-4 Protein, Human (HEK293, His) P31431-1 (E19-E145) ≥95%

关联疾病

疾病名称 别名
Thyroid Carcinoma

Thyroid Cancer

Malignant Neoplasm Of Thyroid

Thyroid Neoplasm

Achromatopsia 7

ACHM7

Achromatopsia, Type 7

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SDC4 VGNC VGNC:98441
Canis familiaris SDC4 VGNC VGNC:45944
Mus musculus SDC4 MGD MGI:1349164
Rattus norvegicus SDC4 RGD RGD:3650
Bos taurus SDC4 VGNC VGNC:34381
Felis catus SDC4 VGNC VGNC:64946
Others SDC4 NCBI