2. Gene
  3. SDC3 - syndecan 3 Gene

SDC3 - syndecan 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：联癸烷 3

种属: Homo sapiens

同用名: SDCN; SYND3

基因 ID: 9672 | 基因类型: protein coding

关于 SDC3

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:30,869,466-30,909,735 (from NCBI)

This gene has 4 transcripts (splice variants), 197 orthologues, 3 paralogues and is associated with 1 phenotype. Broad expression in brain (RPKM 64.6), spleen (RPKM 56.5) and 21 other tissues.

功能概要

该基因编码的蛋白质属于聚糖蛋白聚糖家族。它可能通过影响肌动蛋白细胞骨架在细胞形状的组织中发挥作用，可能是通过以糖依赖性机制从细胞表面传递信号。该基因的等位基因变异与肥胖有关。[RefSeq 提供，2009 年 10 月]

The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin Cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]

SDC3 基因产物(1)

mRNA Protein Name
NM_014654.4 NP_055469.3 syndecan-3 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18093920 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18093920 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SDC3 蛋白结构

Syndecan

Syndecan: Syndecan domain (377 - 440)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 442 a.a.
蛋白主名 其他名称

syndecan-3

N-syndecan

SDC3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SDC3 O75056 SDC2 Homo sapiens P34741
Comigration in Gel
18093920
种属内
SDC3 O75056 SDC4 Homo sapiens P31431
Comigration in Gel
18093920
种属内
SDC3 O75056 RPS4Y1 Homo sapiens P22090
Anti Tag CoIP
33961781
种属内
SDC3 O75056 SDC3 Homo sapiens O75056
Comigration in Gel
18093920
种属内
SDC3 O75056 SDC3 Homo sapiens O75056
ToxCat
18093920
种属内
SDC3 O75056 MYZAP Homo sapiens P0CAP1
Anti Tag CoIP
33961781
种属内
SDC3 O75056 KRTAP5-9 Homo sapiens P26371
Y2H Array
31515488
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 SDC3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73624 Syndecan-3 Protein, Human (HEK293, His) ABM82826 (M1-K311) ≥95%

关联疾病

疾病名称 别名
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Alcohol-Induced Mental Disorder

Psychoses, Alcoholic
Muscular Dystrophy

Muscular Dystrophies

Congenital Md

Congenital Muscular Dystrophy

Cmd

Mdc

Dystrophy, Muscular

Gower'S Muscular Dystrophy

Progressive Musclular Dystrophy

Pseudohypertrophic Atrophy

Pseudohypertrophic Muscle Paralysis

Pseudohypertrophic Muscular Atrophy

Pseudohypertrophic Muscular Dystrophy

Pseudohypertrophic Paralysis

Pseudomuscular Hypertrophy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12581 SDC3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SDC3 MGD MGI:1349163
Macaca mulatta SDC3 VGNC VGNC:76999
Bos taurus SDC3 VGNC VGNC:34380
Canis familiaris SDC3 VGNC VGNC:45943
Felis catus SDC3 VGNC VGNC:64945
Rattus norvegicus SDC3 RGD RGD:621486
Others SDC3 NCBI
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