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  2. SDC3 - syndecan 3 Gene

SDC3 - syndecan 3 Gene

中文名称:联癸烷 3

种属: Homo sapiens

同用名: SDCN; SYND3

基因 ID: 9672 | 基因类型: protein coding

关于 SDC3

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:30,869,466-30,909,735 (from NCBI)

This gene has 4 transcripts (splice variants), 197 orthologues, 3 paralogues and is associated with 1 phenotype. Broad expression in brain (RPKM 64.6), spleen (RPKM 56.5) and 21 other tissues.

功能概要

该基因编码的蛋白质属于聚糖蛋白聚糖家族。它可能通过影响肌动蛋白细胞骨架在细胞形状的组织中发挥作用,可能是通过以糖依赖性机制从细胞表面传递信号。该基因的等位基因变异与肥胖有关。[RefSeq 提供,2009 年 10 月]

The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin Cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]

SDC3 基因产物(1)

mRNA Protein Name
NM_014654.4 NP_055469.3 syndecan-3 precursor

SDC3 蛋白结构

Syndecan

Syndecan: Syndecan domain (377 - 440)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 442 a.a.
蛋白主名 其他名称

syndecan-3

N-syndecan

重组 SDC3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73624 Syndecan-3 Protein, Human (HEK293, His) ABM82826 (M1-K311) ≥95%

关联疾病

疾病名称 别名
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Alcohol-Induced Mental Disorder

Psychoses, Alcoholic

Muscular Dystrophy

Muscular Dystrophies

Congenital Md

Congenital Muscular Dystrophy

Cmd

Mdc

Dystrophy, Muscular

Gower'S Muscular Dystrophy

Progressive Musclular Dystrophy

Pseudohypertrophic Atrophy

Pseudohypertrophic Muscle Paralysis

Pseudohypertrophic Muscular Atrophy

Pseudohypertrophic Muscular Dystrophy

Pseudohypertrophic Paralysis

Pseudomuscular Hypertrophy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus SDC3 MGD MGI:1349163
Macaca mulatta SDC3 VGNC VGNC:76999
Bos taurus SDC3 VGNC VGNC:34380
Canis familiaris SDC3 VGNC VGNC:45943
Felis catus SDC3 VGNC VGNC:64945
Rattus norvegicus SDC3 RGD RGD:621486
Others SDC3 NCBI